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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '758204133fc9ae9e64d665e753a6b36e4496b74620607e3b0120172a4017fb6a' 
  AND token = '5Xs5G7Zkrt0Q4mAyEJCZ+fUpDPHbaDyPDUd4afsLMXI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}