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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8fc1fd68f672d3a707993ca1fd94072d6cfbd9dcfab3bc751bb6f26bbe7b7942' 
  AND token = 'WD4lWpHV+SYaHVaUqegYMEN5II802+Qr21EFOVzqh0I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}