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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2d240393fef3d633461201af67429dba6ef089b013d8f20a8104e3be6a94036' 
  AND token = '8F9G+ucmtcpCpUThxRDYm7BrR4mkK82C76dZonP35jA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}