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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c407788d3a28563681eb79fe7ad231cb2385cc62654473115f981adf13167b8' 
  AND token = '/FRSiRwBpa0Cb5Bo+kG8165fnD+4gFuezaxz0XmNQnY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}