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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed593b06ce960a6aab66b3b5c52caf94653bd8da1c191f6ba7e1a20f1cf74b54' 
  AND token = 'POcTlBA9F3FCNLujN1MXFSMZ/kpyqWt5fwiGqZ0oyqM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}