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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f8c38d0e5fa7352a9833e3d04a43b5d128911d39d8bbd5bd1f081927510b4c73' 
  AND token = 'duRJaho/OLJSTyNgYkF4cC81+sPq7QWfeUXa8sY1kj8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}