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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d41d11c724aa11247e4f4ea7775ecb56a70624ba59cbce465ac433a8b058a65' 
  AND token = 'y+EPvw1pa2rb2udwA4MpXYQJFcA9G09igdP3yALnf6c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}