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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dde1e527781db63c56c842eb58eff0fa57d9132ab1f693eb3b93a553703b9d44' 
  AND token = 'ku+TjJcJWcnnJ6aD6TZY/rQRVni9+BrX8cFtxZb3uO4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}