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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b181eb0724a2e8243871a407615f4a91cbc407e11d4a5f014654da4e66ff74be' 
  AND token = 'tHks0NoYKAjRlTbffts1I9+vdX4cWu9NhB3ejGj9yck=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}