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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74ce72930728a53aae97f30668a2843a9373b1bfb58ab6fe6e3f2cd2a33a6af9' 
  AND token = 'lD0wXOWYax+TluTe+6QL0owORcEniXv51OmnI4VYAWs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}