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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '276a3c58249cab41e1555057e6daaaa298119bdd2872fe95f073eede4c6171a0' 
  AND token = 'VKkCf4xWOXjO6p3g99PaT10E0CTS6zQyJ//gMOYT+ZI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}