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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cfb80710c9d678bc78a535f69ea89d71b15821dc36adb47b3a3fc78cfba377eb' 
  AND token = 'ZclFQbEcBvll2e6hR4HuHqICxl1G2XlDY++r4kbRr5o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}