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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '69486aaf940a37c945f58689f304629287ece3fcee05db865f34c8d27b817de8' 
  AND token = 'tCPCwcA9/tlVjwLiN2KsDbu2UpswMkMATNQs9TQDKVY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}