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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8cccbc9949b23f8a86fb8f991bbcd0d65c0493af815e4bac725d01b1ffdf7265' 
  AND token = '6/cH/3nvBFLfzDERxqPZsZkZeY219dv8inpAIX3oj8g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}