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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b948045cfa5042cf49d71d74bf734e7a0b7b2c39b21e63b40594741f2545e973' 
  AND token = 'uw2mxpZCDRArPn/YyZfoe8Z9GLy3nzTmTbA2yG7BqTQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}