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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '443c35a356ff6bbb97958bf45de3ae8d23205c9b44358179b5076218e0e9de3a' 
  AND token = 'LRUHHiO385DYcxkQggZuJ3aAVD5+05uKt2Moc8OowNc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}