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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bb53ddf8925c4f8bf3843451d5018f3eac5a08ce6d675e02568e6fd54f46a31d' 
  AND token = 'IEOPxawxMpB5fm/xC+l+LfpNO6RYudARobNRLflj4W8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}