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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '361972c116fa4803dec43a3ba72fbd46290171007c83a61794dbb5dd666d2e6b' 
  AND token = 'FpQHbAp5dcjlGS0ekKzpHwhjkPUkfgAnkNvnwdm3dho=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}