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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '160f82baf619e4edb0fa9590beae269b3f2b2f8249ddfcce64cb9eb464afdf2d' 
  AND token = 'p4+Xsi9xNwSt7qdY9gddULij9cIQR8LN4hrTaXHept8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}