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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10a6f6c5c73789b775b6ecc1f69762b781b0cc59b6a05a4d68bf5ab14d6395e1' 
  AND token = 'q5GpdAkyXAJKFnaU726pKsbPqxTtkCNB/FkyXhhbv98=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}