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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1907ec9059aa18dd1625134ae926a9dc519751eca82739981d5c08aec8dfc837' 
  AND token = 'EC2evmo7O4UL4QUDBkT20qh1REYlkMYp+vYziI5WBd0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}