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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bb47c4ecd3706093685acf0f42994985ed3f99094a8c336e3b43b4f263d7b017' 
  AND token = 'p8nM/O2uvE4dqlIpVTm+CVwRD/KfSOz3LnUFIil4/Ew=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}