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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd76165cd20302cb6dd1661459a8cb08d9f00612c03b4a1d7df7ae8343d45b92d' 
  AND token = 'VhOE+Ma98jS8Xg/dC/qG0Bf7kAc2IufhkVQ7Q09570g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}