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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2abbbe9c75b0fda35d591bc3d53315dfe9ad084f65be4c0e8046e951f4c461e7' 
  AND token = '+EV3pvPNhg9/ns6HncIv6rwPDhdImLrMUBHS9CJ9hHo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}