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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a61d2a91d3f35148212a2a0cde31c425ad9c6a4a65681ca5affc9bc416e79408' 
  AND token = 'Q5cjvSJIzHaTDjS+WWtL3RqZ3pXDopkdzLIzEXSUS78=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}