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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f86013168b355bc8bb9d1071753379e4e27305f7facab4ed8b83a7cc44dbed6' 
  AND token = 'Si+r74SLyVst/TiUt7TYJkfdpjnThnEcW2D3unUDlwI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}