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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '62c101117ad23e6c7192119a05b0c6052b2c31d3b4f3df78b4aa2a22477ff05c' 
  AND token = 'o5gayDXI3/NiIU6vrWkbmiLg07SeCHBAGHs36bRO2MQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}