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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b4a60d96b3125060a40a0b4b800bac53e3dc7f7acff25da3c61bc3e76cc7d83e' 
  AND token = 'yvCLy2oW19W22IesDTSH2DMpC5poj7raE61xfJMtfnw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}