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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4573d2ff7f8fc8e5d4a5dcd549f3e2a0e2092a13a0b52bae0481b9e15c60e3cc' 
  AND token = 'GdAOTubh+2Two5dmOr9Lyn3ox5raEa6Vsj6u1bcnwgg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}