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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '263597143b44536a18f8b276080fe982ad370fdaa4e2f8dbbf79ec1c558d7551' 
  AND token = 'S4+aOKMR1Q1f7MNkY7Y8Khj+tS9iOagDJtuV8nQisHw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}