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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6900181ade05c60169ecd2fd2af7c4880b221d5fedae0f366a7a7a2d6fd8d455' 
  AND token = 'Qxo9zr81GJ7uPt3ak4fokXjXM7BDmP8ChGT2GHFvZwg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}