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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '481c4901d4ad126db2ffe5825c4aaf418432a11584a4ded75f09bdbb716d102e' 
  AND token = 'YiQz8WlIZ+cem79pyvLqLlCdB50+xuNgfOS8c63f6ZE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}