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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f8ed4664a5134ad7bf2e3743542a6676a9a5548962c05003d721e01ac26d4c8' 
  AND token = 'fSrk9aeyUtedMKFl7hNzafYBedXWAorhXCLzt7JjD74=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}