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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a7b8e0328fdf99eafc0600b95fb4eeb3831143b6eede1434fe5358ed54e90d4' 
  AND token = 'HJIB+OhNZ6HZ4rzmpWZMIToD5oDQ/DMKNWjFhZZ6nvo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}