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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2cf565130b32e4b7f72146914fa7ddd933f12e546caa7c10debeed232d91029a' 
  AND token = 'arrlpzVWq7XYG+FiuRPMpf8fv0poe5iFfZf8nR8+Uko=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}