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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e94f9001d2c4efd229840542cb800fe8baad82475501a10a1e17a37e94dd482c' 
  AND token = 'YD0VROq5wJ2QzN58sIGOWsQVpOoAG8oGOqE0YV4O6PQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}