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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ca0913a0daaa71f3e9999dba0982d7146f47eabd1f9f921da475be291b53670' 
  AND token = 'vMx6OyMjGQbkc9jp/NdJpVMCO4NY+IcYG1UsAFCLQ1E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}