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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'da90fdb07be6d267546a5881a0a6f40246f79150fe3567594679f7b8b367bf56' 
  AND token = 'uumIUsxHF5F8PFr0oAcRFMrhpHEDOFC5g/cAtEXDocM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}