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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00c8223000baad7b9d5d7fa07cb3b6f5abed50f5ede32fd8926e65f6e2720d90' 
  AND token = 'rCbGypTQ98rkzcFOniqkitpcyUDbZqdxppsBZ+ebgUM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}