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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c1b649c485442bf162adf2ceb8df957d1166c18c852048ad2284c026b3933c3' 
  AND token = '06KyoUXTZ6JM606DdgIn40LxbKUJa7EyKSDcr7V4g9Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}