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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a2c749f5c64c96eaf9d702e6a5916a904e89ac4991254ea11be5947ef90de2f' 
  AND token = 'UZqK76/tc6MBnvsx3qzdMn+GxWcO5cPc0+aoKlv1nMw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}