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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a15a54fc42acd6cc777741964eb2c03a13b73481065040b489d170142f17ce2c' 
  AND token = 'syszJDSdxTghsU1JRTQ5uPY39i/TCno6e0jbkZJ7MOM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}