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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3b24f1a8840d9034e822b33522a4aae3d1192db6cbf6beb507fed0222e4683f6' 
  AND token = 'vVaSnfxIdtd/Jm/nswd2yVHPq8r0QlrcxqbpP6gABgY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}