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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a43e17913e77d3fc74c136d0f162b5ec040743a4182f897e52f8e27391d1e1a9' 
  AND token = 'R/++zOo4n4eWY5L7V/Swk+mqvE/VyZkMDaDVfqocRoQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}