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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a7281f8971eb9c39ddfd95960f74c31d0d799378cbc11a7c1efa1bbe2b4d1eb0' 
  AND token = 'xu4CjOZlhvcXEr4G+M6djmfikyd+fex8lIFgXO1JoX4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}