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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b9cea21b9d0a99c3696a8c55679e1a06c5a7105df31c7f4bdcb429159afb53a' 
  AND token = 'MqP+JDg1DcTJCTaL9/De7P9VPJV8btqbILvvE3LP3j8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}