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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '86d8f2451bcf0e024ad59a62f79e9eec37fbfd0450f73471a41b4110d94cb4e1' 
  AND token = 'JV0O7ywrappnajfFtcywT7r2UOmVmg+YKvNLLSVBYs8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}