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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fa6f750be332a8a8bb5c8cc7e040436c8da31ffa1c9f5aeab7e348620bffd556' 
  AND token = 'bvqP3+AFCINybVn2h8gEmgOwal9wZE4pqOYVI6Eommc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}