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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8204a78656ac39bdeed04941b0b2e81cd5f2193a55925ab24754f45a0a5c65c6' 
  AND token = '8GOM7RtmPptah1QpnLfhXFfyWMArQWTXARM+JF3ySuA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}