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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca50ea72a8047fadd58b133b5fc98ff916f9f0bbec31ca15a3775a2853019c95' 
  AND token = 'JE/BaUCpq/V7xnAfVdNoZTVD32sO91fz4WX0+D1u/7M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}